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Acid Reflux on GLP-1: Quick Tips
Acid Reflux and Heartburn from Zepbound, Mounjaro, Ozempic and Wegovy? Here’s How to Fix It
Digestive side effects like acid reflux or heartburn can sometimes put a damper on things. This post breaks down some quick, actionable tips to help you manage acid reflux while on your GLP-1 therapy.
Work with your physician to determine the best symptom management approaches, and always do so before modifying your medication regimen.
Basic Strategies
Posture awareness: Maintain upright position during and after meals
Elevated sleeping: Raise the head of your bed 6-8 inches or use a wedge pillow
Meal timing: Avoid eating within 3 hours of bedtime
Portion control: Eat smaller meals more frequently throughout the day
Loose clothing: Wear non-restrictive clothing, especially around the waistline
Weight management: Continue healthy weight loss journey with your GLP-1 medication
Smoking cessation: Avoid smoking and tobacco products which worsen reflux
By Severity Level
Mild Reflux
Food diary: Track foods and activities that trigger symptoms
Chewing thoroughly: Take time to chew each bite 20-30 times
Drinking habits: Sip water between meals rather than with meals
Post-meal walking: Take a gentle 10-15 minute walk after eating
Herbal teas: Caffeine-free chamomile, licorice, or marshmallow root tea
Stress reduction: Practice relaxation techniques before or after meals
Moderate Reflux
OTC medications: Occasional use of antacids or H2 blockers (with doctor's approval)
Meal spacing: Allow 4-5 hours between meals for complete digestion
Sleep positioning: Sleep on left side to reduce reflux during night
Slippery elm: Consider supplements to coat and protect esophagus
Abdominal breathing: Practice diaphragmatic breathing exercises
Pre-meal preparation: Take 1 tsp apple cider vinegar in water before meals (if appropriate)
Severe/Persistent Reflux
Medical evaluation: Consult doctor to rule out GERD, hiatal hernia, or erosive esophagitis
Medication review: Discuss timing and dosage of GLP-1 medication with your doctor
Prescription options: Consider prescription-strength acid suppressants if approved
Specialized testing: Ask about pH monitoring or endoscopy if symptoms persist
Physical therapy: Evaluation for potential diaphragmatic strengthening exercises
Advanced treatment: Discuss procedures like fundoplication if severe and unresponsive
Dietary Modifications
Eliminate triggers: Avoid classic reflux triggers (caffeine, chocolate, alcohol, citrus, tomatoes)
Limit acidic foods: Reduce intake of highly acidic foods and beverages
Moderate fats: Limit fatty, fried, and greasy foods that delay stomach emptying
Spice adjustment: Reduce or eliminate spicy foods, especially in evening meals
Food combining: Experiment with proper food combining techniques
Alkaline balance: Incorporate more alkaline foods like leafy greens and non-citrus fruits
Carb quality: Choose complex carbohydrates over simple, refined options
Lifestyle Adjustments
Meal spacing: Space meals evenly throughout the day, avoiding large gaps
Hydration timing: Drink fluids between meals rather than with meals
Sleep schedule: Maintain consistent sleep-wake cycles
Stress management: Practice regular stress-reduction techniques
Exercise timing: Avoid vigorous exercise within 2 hours of eating
Breathing exercises: Practice diaphragmatic breathing for 5-10 minutes daily
Posture training: Work on posture exercises to reduce abdominal pressure
Complementary Approaches
Ginger: Use fresh or as a supplement to aid digestion (1-2g daily)
DGL licorice: Take deglycyrrhizinated licorice tablets before meals
Aloe vera: Consider pure aloe vera juice (2-3 oz) between meals
Acupuncture: Traditional treatment for digestive disorders
Probiotics: Specific strains that may help with digestion and gut health
Melatonin: Low-dose supplement at bedtime may help strengthen esophageal sphincter
Zinc carnosine: Supports healing of gastric and esophageal tissue
Quick Relief Techniques
Baking soda: 1/2 teaspoon in 4 oz water for immediate acid neutralization (occasional use only)
Gum chewing: Chew sugar-free gum for 30 minutes after meals to stimulate saliva
Upright position: Stand or sit upright for at least 30 minutes after eating
Loose clothing: Immediately loosen tight belts or restrictive clothing
Calcium-based antacids: Provide quick relief and additional calcium (with doctor's approval)
Arm raising: Raise arms above head for 1-2 minutes to relieve pressure
Herbal lozenges: Slippery elm or marshmallow root lozenges to coat throat
Nighttime Strategies
Dinner timing: Eat dinner at least 3-4 hours before bedtime
Elevate head: Use bed risers or a wedge pillow (not just extra regular pillows)
Left side sleeping: Sleep on your left side to reduce reflux episodes
Pre-bed routine: Avoid screen time and practice relaxation before bed
Avoid water: Don't drink large amounts of water right before sleeping
Light snack option: If needed, choose a small protein-based snack instead of carbs
Pajama choice: Wear loose-fitting nightwear that doesn't constrict abdomen
Remember that reflux symptoms often improve as your body adjusts to GLP-1 medications and as weight loss progresses. However, persistent or severe reflux requires medical attention to prevent complications like esophageal damage.
When to Contact Your Doctor
Reflux symptoms persist despite implementing management strategies
You experience difficulty swallowing or painful swallowing
You notice unexplained weight loss or decreased appetite
You have persistent hoarseness, chronic cough, or worsening asthma
You experience chest pain (after cardiac causes have been ruled out)
You notice black, tarry stools or vomiting with blood
If you find this post useful, copy the link and share it with someone else walking the GLP-1 path. Every new reader who joins our email list makes a difference.
Stay healthy (and hungry for knowledge),
Lucas Veritas
![]() | I’m a true GLP-1 believer. Background: Lost 90+ lbs. Found energy. Gained clarity. Read about me or get in touch Must Reads: explore most popular posts. Resource Directory: a selection of useful links for anyone on GLP-1 shots |
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